Cytotoxic effects of antimony trichloride on mice in vivo
Gurnani, N.; Sharma, A.; Talukder, G.
Cytobios 70(281): 131-136
1992
ISSN/ISBN: 0011-4529 PMID: 1451533 Document Number: 403456
Clastogenic effects of antimony trichloride, used in small industries, were monitored in laboratory bred white Swiss mice in vivo, following oral administration by gavaging, after 6, 12, 18 and 24 h. Chromosomal aberrations were principally breaks and damaged cells observed from bone marrow preparations. The frequencies of chromosomal aberrations were directly related to the dose used and were significantly higher than the control. The chemical did not alter the frequency of dividing cells to any significant level.
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