Colonic fermentation in humans: effect of the ingestion of meat associated to milk
Solomons, N.W.; Castillo, C.; Guerrero, A.M.
Revista Medica de Chile 120(8): 858-861
1992
ISSN/ISBN: 0034-9887 PMID: 1340958 Document Number: 402644
The amount of expiratory H2 produced for 6 h following the ingestion of milk 240 ml was used as an index of the rate of colonic fermentation of undigested lactose in 8 lactase non-persistent Guatemalan adults. Treatments in separate days included milk alone, milk with cooked beef 400 g, lactose pre-hydrolysed milk with the same amount of beef, beef alone and fasting for 6 h. Excess excretion of H2, calculated as the mean area under the curve was 178+or-31 with milk alone, 50+or-17 with milk plus beef and -1+or-26 ppm/h with prehydrolysed milk. Peak increments of respiratory H2 followed the same trend: all subjects had values greater than 20 ppm with milk alone, 2 with milk plus beef and none with hydrolysed milk, beef alone or fasting. Thus, cooked beef significantly reduces the rate of appearance of intact lactose in the large bowel of lactase deficient adults.