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Excessive cicatrization after glaucoma-control operations: the participation of plasma fibronectin

Lebedev, O.I.

Vestnik Oftalmologii 108(4-6): 9-11

1992

ISSN/ISBN: 0042-465X
PMID: 1295200
Document Number: 397875
Based on the results of examinations of 300 patients with primary glaucoma after trabeculectomy, the author has developed clinical criteria for the evaluation of the intensity of the reparative processes at the site of intervention. Plasma fibronectin levels were found to grow with the progress of glaucoma (from Stage I to Stage II almost twofold). Analysis of correlations and regressions has revealed reliable relationships between plasma fibronectin levels and clinical values of the intensity of reparative processes at the site of surgery. Preoperative measurements of plasma fibronectin help predict with a high degree of probability the hypotensive effect of surgery.

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