Antiarrhythmic active amidinohydrazones of substituted benzophenones. 3. the isomerization of (E) -2-amino-5-chlorobenzophenone amidinohydrazones
Richter, P.H.; Besch, A.; Albrecht, D.; Kasbohm, K.
Die Pharmazie 47(12): 911-914
1992
ISSN/ISBN: 0031-7144 PMID: 1293613 Document Number: 396816
The isomerization of the title compound in a preparative scale can be realized by acetylation/deacetylation or by influence of protons in dimethylformamide. The title compound is obtained als main product of the condensation of 2-amino-5-chlorbenzophenone and aminoguanidine if the reaction is carried out in the presence of formaldehyde.
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