Disseminated zygomycosis in patients with acute leukemia
Marisavljević, D.; Suvajdzić, N.; Jovanović, V.; Kranjcić-Zec, I.; Bosković, D.; Colović, M.
Srpski Arhiv Za Celokupno Lekarstvo 120(1-2): 65-69
1992
ISSN/ISBN: 0370-8179 PMID: 1641704 Document Number: 396409
The authors present two patients with acute myeloid leukaemia and pulmonary-disseminated form of zygomycosis developed during the period of bone marrow aplasia. Diagnosis was established on necropsy on the basic of the patho-histological finding of wide, short and nonseptate hyphe with irregular branching. Hyphe were clearly recognized on Gomori methenamine Silver stained preparations. There were multiple haemorrhagic-necrotic infarcts of different organs due to the mycotic invasion of blood vessels. The authors discuss some some important diagnostic and therapeutic problems.
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