The pharmacological regulation of neutrophil activity by cholinotropic preparations, barbiturates and fenazepam
Zabrodskiĭ, P.F.
Eksperimental'naia i Klinicheskaia Farmakologiia 55(6): 31-33
1992
ISSN/ISBN: 0869-2092 PMID: 1363955 Document Number: 392698
The in vitro experiments with human blood cells and in vivo experiments on Wistar rats have demonstrated that stimulation of neutrophils enhances their phagocytic metabolic activity. Barbiturates (benzonal and phenobarbital) and phenazepam in low concentrations (doses) increase neutrophilic function evaluated by the NBT test, but in high ones cause opposite effects.
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