Effect of dietary salt (NaCl) supplementation on urinary profile of guinea pigs (Cavia porcellus)
Singh, P.P.; Hussain, F.; Gupta, R.C.; Pendse, A.K.
Indian Journal of Experimental Biology 30(5): 443-444
1992
ISSN/ISBN: 0019-5189 PMID: 1459625 Document Number: 391680
Sodium chloride supplementation (120 mg/kg of body weight/day) for 12 days increased the urinary excretion of calcium from 91.6 +/- 9.0 to 159.4 +/- 16.0 mumol/day and of sulphate from 266.8 +/- 24.5 to 1176.9 +/- 87.2 mumol/day in guinea pigs. The stone risk due to increased urinary calcium excretion could possibly be counterbalanced by increasing urinary sulphate excretion. High salt intake, thus, could not increase the risk of stone formation.