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The effect of streptase in hypoxia on the blood and abdominal aorta in rats

Pustovalov, A.P.; Voronkov, I.F.

Farmakologiia i Toksikologiia 54(3): 43-45

1991

ISSN/ISBN: 0014-8318
PMID: 1833237
Document Number: 387434
In the experiment of albino rats it was shown that hypobaric hypoxia caused a disorders of hemostasis with destabilization of membranes and imbalance of electrolytes in the erythrocyte-plasma-vessel wall system. Streptase administration in a dose of 2500 U/kg in this case events in some degree the changes in the process of the blood coagulation, viscosity-elasticity properties of erythrocytes, calcium levels in plasma and erythrocytes, sodium and magnium levels in the abdominal aorta wall produced by the "altitude rise" in an altitude chamber.

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