Effect of early postnatal hypoxia on Wistar and August rats
Krupitskaia, L.I.; Tseĭlikman, V.E.; Popova, A.S.; Sinitskiĭ, A.I.; Gornostaeva, A.B.
Rossiiskii Fiziologicheskii Zhurnal Imeni I.M. Sechenova 95(7): 773-778
2009
ISSN/ISBN: 0869-8139 PMID: 19803463 Document Number: 630965
It was proved that hypoxia tolerance often goes together with forming of oxidative stress tolerance and has genetic predetermination on hypoxic influence. Interline difference ofhypoxia sensitivity is mainly defined by difference of oxygen-transport systems state. Genetically predetermined differences between investigated lines give the August rats the ability to use mechanisms of resistant strategy more effectively, and the Wistar rats--to use tolerant strategy more effectively.