Methods in determination of selenium states
Nève, J.
Journal of Trace Elements and Electrolytes in Health and Disease 5(1): 1-17
1991
ISSN/ISBN: 0931-2838 PMID: 1822321 Document Number: 378309
Selenium status in man has been assessed either by determination of the selenium concentration in biological materials or by the measurement of biochemical or clinical selenium-dependent functions. Over and above the discussion of normal levels and of the numerous factors liable to influence the above mentioned indices, the present review more specifically deals with the sensitivity of various parameters to changing selenium status, both in deficiency states and in over-exposure to the element, and the attempt is made to establish the specificity of these indicators in the diagnosis of selenium states. The possibilities for defining "adequate" or "optimum" selenium concentrations are also examined.