A clinical study on cefdinir in pediatric field
Fujita, M.
Japanese Journal of Antibiotics 44(10): 1083-1086
1991
ISSN/ISBN: 0368-2781 PMID: 1762165 Document Number: 373876
Cefdinir (CFDN) was administered to pediatric patients with acute infectious diseases. A summary of the results obtained is as follows. 1. Pharmacokinetic parameters were determined in a girl. In comparison to reported data in adults, Tmax was shorter, Cmax was slightly lower, and the plasma half life of CFDN was somewhat longer. 2. Clinical efficacy was studied in 11 children with acute tonsillitis (6 patients), scarlet fever (1 patient), acute pharyngitis (1 patient), acute pneumonia (1 patient), acute otitis media (1 patient) and acute cervical lymphadenitis (1 patient). Responses to the treatment were excellent in 7 (63.6%) and good in 2 (18.2%). 3. No adverse reactions were noted in this study.