Clinical studies of T-1982 (cefbuperazone) in pediatric field
Aoyama, R.; Waga, S.; Ohnishi, A.; Izumi, Y.
Japanese Journal of Antibiotics 36(4): 736-738
1983
ISSN/ISBN: 0368-2781 PMID: 6876375 Document Number: 207115
T-1982 (cefbuperazone) is a newly developed cephamycin. Clinical studies on this drug were carried out and the results were as follows: Eighteen patients (pneumonia 13, purulent tonsillitis 1, acute bronchitis 1, cellulitis 1, urinary tract infection 2) were treated intravenously with daily 27.4-100.2 mg/kg of T-1982 in 3-4 divided dose for 3-6.7 days. The overall efficacy rate was 94.4%. No adverse reactions were observed. Abnormal laboratory data noted were liver dysfunction in 1 case (4.8%), eosinophilia in 2 cases (9.5%), and anemia in 1 case (4.8%).