A clinical study of PC-904 in pediatric field
Aoyama, R.; Nagata, K.; Izumi, Y.; Kudo, M.; Sato, S.
Japanese Journal of Antibiotics 31(7): 363-365
1978
ISSN/ISBN: 0368-2781 PMID: 691259 Document Number: 134894
A clinical study of PC-904 was performed and the following results were obtained. 1) PC-904 was intravenously administered at the daily dosage of 20 approximately 120 mg/kg to 13 children; urinary tract infection (10 cases), acute pneumonia (1 case), sepsis (1 case) and purulent meningitis (1 case). The overall efficacy rate was 46.2%. 2) As to adverse reaction, eosinophilia was noted only in 2 patients. One neonate was treated with this drug, but no side effects were observed. 3) It was considered that PC-904 was a useful antibiotic drug for the second choice rather than the first.