Effects of buspirone on the immunosuppressive response to stress in mice

Freire-Garabal, M.; Belmonte, A.; Suárez-Quintanilla, J.

Archives Internationales de Pharmacodynamie et de Therapie 314: 160-168

1991


ISSN/ISBN: 0003-9780
PMID: 1668602
Document Number: 370649
Mice exposed to a chronic auditory stressor and treated with buspirone (1 mg/kg/day) showed a reduction in stress-induced suppression of thymus and spleen cellularity, and in peripheral T-lymphocyte population. The blastic response of spleen lymphoid cells was also assessed and buspirone was found to partially suppress the inhibitory effect of stress.

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