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Gastric cytomedines effects on immune response in acute immobilization stress in rats

Shcherbak, V.A.; Malezhik, L.P.; Aksenova, T.A.; Pateiuk, A.V.

Patologicheskaia Fiziologiia i Eksperimental'naia Terapiia 3: 6-7

2005

ISSN/ISBN: 0031-2991
PMID: 16206518
Document Number: 588773
Effects of gastric cytomedines on repair and immune response were studied in 137 white non-inbred rats. Erosions of gastric mucosa were induced by acute immobilization stress. A decrease in antibody production, titers of hemagglutinins and hemolysins was found on day 2 after stress. Gastric cytomedines in a dose 0.15 mg/kg intramuscularly stimulate immune response (increased production of antibodies, antibody dependent cellular cytotoxicity index, titers of hemagglutinins and hemolysins), fast erosions epithelization and have a protective action.

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