Effects of buspirone on the resistance, development and passive transfer of immunity to Listeria monocytogenes in mice submitted to stress
Freire-Garabal, M.; Nuñez, M.J.; Fernandez-Rial, J.C.; Rey-Mendez, M.; Belmonte, A.
Archives Internationales de Pharmacodynamie et de Therapie 324: 114-123
1993
ISSN/ISBN: 0003-9780 PMID: 8297183 Document Number: 410117
Mice exposed to a chronic auditory stressor and treated chronically with buspirone (1 mg/kg) showed a reduction in stress-induced suppression of the resistance and development of immunity to Listeria monocytogenes. Attempts to passively transfer immunity with spleen cells were also performed. Stressed, immunized mice had a reduced capacity to transfer immunity passively to nonimmunized mice and buspirone was found to partially suppress this inhibitory effect of stress.