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Multifactorial experiment on the combined effect of rifampicin and microbial polysaccharide in experimental plague infection

Nikitin, A.V.; Makarovskaia, L.N.; Fomina, I.P.; Ivanitskaia, L.P.; Popova, G.O.; Vinidchenko, N.N.; Korganov, I.N.; Gorin, S.E.

Antibiotiki i Khimioterapiia 36(5): 25-27

1991

ISSN/ISBN: 0235-2990
PMID: 1953167
Document Number: 370380
Multifactorial analysis was applied to the study of the combined effect of rifampicin and a microbial polysaccharide in experimental plague infection. The effect of the antibiotic and immunomodulator was shown to be synergistic. On the basis of the study results polynomial statistic models of the second order were designed and nomograms or equal level lines were plotted which provided optimization of the combined chemo- and immunotherapy.

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Nikitin, A.V.; Makarovskaia, L.N.; Fomina, I.P.; Ivanitskaia, L.P.; Popova, G.O.; Vinidchenko, N.N.; Korganov, I.N.; Kudinova, M.K. 1991: A multifactorial analysis of the combined action of an antibiotic and a low-molecular immunomodulator of microbial origin in experimental plague infection Antibiotiki i Khimioterapiia 36(6): 41-43
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