Indices of structure and function of erythrocyte membranes in rats with vitamin E deficiency and their correction with antioxidant drugs
Poberezkina, N.B.; Khmelevskiĭ, I.V.
Ukrainskii Biokhimicheskii Zhurnal 62(6): 105-108
1990
ISSN/ISBN: 0201-8470 PMID: 1965070 Document Number: 367579
It is found that the amount of saturated fatty acids grows, while that of unsaturated--falls in the erythrocyte membranes of rats maintained on a diet without vitamin E. In this case transmembrane calcium transport catalyzed by Ca2(+)-ATPase (EC 3.6.1.3) is not broken and activity of antioxidant enzyme superoxide dismutase (EC 1.15.1.11) in lysate of erythrocytes falls. The found shifts are corrected with administration of antioxidant preparations.