Acrosyringium and follicular infundibulum: immunomorphologic aspects
Niedecken, H.W.; Biwer, E.; Bauer, R.; Kreysel, H.W.
Zeitschrift für Hautkrankheiten 65(6): 578-581
1990
ISSN/ISBN: 0301-0481 PMID: 1697133 Document Number: 365811
Acrosyringium and infundibulum are epidermal structures with different morphology, but functional similarities regarding re-epithelialization, transport of antigens, and attraction of infiltrates. Immunomorphologically, the infundibula revealed an immunoreactivity of Langerhans cells and keratinocytes comparable with that of the interfollicular epidermis, whereas the acrosyringia reacted differently because of the permanent expression of MHC class II antigens and reduced Langerhans cells in the perisyringial region. Our findings suggest that these epidermal compartments differ with regard to their individual immunologic situations. While the mechanisms of epidermal immunity known from the interfollicular epidermis are possibly the same in the infundibula, we have to expect a basically different immunologic situation in the acrosyringia.