Inhibitory effect of charcoal-treated porcine follicular fluid upon serum FSH levels and follicular development in the rhesus monkey
Channing, C.P.; Anderson, L.D.; Hodgen, G.D.
Advances in Experimental Medicine and Biology 112: 407-415
1979
ISSN/ISBN: 0065-2598 PMID: 111474 Document Number: 142378
Injection of charcoal treated porcine follicular fluid into 4 intact, 4 long term castrate and 2 postmenopausal rhesus monkeys brought about a selective decline in serum FSH levels. Luteinizing hormone levels were not significantly decreased. Intraperitoneal injection of 4 ml porcine follicular fluid every 8 hours for the first 4 days of the menstrual cycle led to a decrease in follicle and granulosa cell growth observed at that midcycle. Treatment with porcine serum did not exert this effect.