Effect of betel chewing on the frequency of sister chromatid exchanges in pregnant women and women using oral contraceptives
Ghosh, P.K.; Ghosh, R.
Cancer Genetics and Cytogenetics 32(2): 211-215
1988
ISSN/ISBN: 0165-4608 PMID: 3365681 DOI: 10.1016/0165-4608(88)90283-xDocument Number: 361409
The incidence of sister chromatid exchange (SCE) was investigated in the lymphocyte chromosomes of betel chewing and non-chewing normal women, pregnant women, and women using oral contraceptives. The frequency of SCE was found to be 7.82 .+-. 0.24 and 8.27 .+-. 0.27 in non-chewing pregnant women and women using oral contraceptives respectively, which were significantly higher than the mean value of 5.21 .+-. 0.18 observed in non-chewing normal women. Betel chewing induced higher SCE in pregnant women and women using oral contraceptives, the frequencies being 11.79 .+-. 0.38 and 12.51 .+-. 0.44, respectively, which were significantly higher than the SCE frequency of 6.28 .+-. 0.21 found in normal betal chewing females.
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