Cardioprotection with drugs. 1: Coronary heart disease
Michel, D.
Fortschritte der Medizin 108(3): 40-44
1990
ISSN/ISBN: 0015-8178 PMID: 1968878 Document Number: 358905
Drug-induced cardioprotection, that is, protection of the heart from injuries of all kinds, is of particular importance in coronary heart disease, especially in fresh myocardial infarction including unstable angina pectoris, within the framework of secondary prevention after infarction, and in chronic coronary insufficiency (stable angina pectoris, silent ischemia). In the case of fresh infarctions, functional myocardium can be protected or salvaged in particular by early thrombolysis, early administration of calcium antagonists or beta blockers (in particular the combination of calcium antagonists with beta blockers). In the area of secondary prevention, beta blockers predominate. In chronic coronary insufficiency, calcium antagonists, nitrates and beta blockers are the first-choice cardioprotective agents.