HIV1 seropositivity and B and D viruses in West Africa
Soubeyrand, J.; Niamkey, E.K.; Ouattara, S.A.; Diallo, D.; Leleu, J.P.; Beda, B.Y.
Pathologie-Biologie 38(9): 899-902
1990
ISSN/ISBN: 0369-8114 PMID: 2177538 Document Number: 357126
This study was undertaken to investigate relationships between three widespread viruses in West Africa, i.e. HIV1 and viruses B and D, in Ivory Coast. Serologic tests for viruses B and D were carried out in a random sample of black adults of both sexes with asymptomatic HIV1 seropositivity. Coinfection by virus B or viruses B and D was a common finding. Coinfection with both viruses B and D, but not with virus B alone, was found to be significantly more frequent in these HIV1-infected adults than in a control group with acute viral hepatitis. Potential interactions between the HIV1 and viruses B and D as well as other viruses are discussed. These findings suggest that one or several cofactors acting alone or in combination play a major role in the clinical expression of HIV infection. The results of this study, together with the suggestion put forward by several investigators that B virus infection may increase the severity of AIDS, are evidence in support of the value of immunization against the B virus in the management of AIDS.