Prognosis factors in adenocarcinoma of the kidney. III. Nuclear area
Gutiérrez, J.L.; Val-Bernal, J.F.; Portillo, J.A.; Garijo, F.; Buelta, L.
Archivos Espanoles de Urologia 43(5): 497-500
1990
ISSN/ISBN: 0004-0614 PMID: 2389974 Document Number: 356480
Nuclear morphometry was performed with the MOP-Videoplan morphometry device in 95 cases of renal adenocarcinoma submitted to radical nephrectomy and hilar lymphadenectomy with a 5-year follow-up. For each case, 100 nuclei were randomly selected and delineated (magnification: 1,000x). A statistically significant correlation (p less than 0.05) was observed for the nuclear area and the overall as well as stage-related survivorship. Using a nuclear size of 35 microns 2, the study population can be divided into two groups: those with a good and those with a poor prognosis regardless of stage. A statistically significant difference was observed for the overall as well as the stage-related survivorship for the group with a nuclear area less than 35 microns 2 (good prognosis) in comparison with the group with a nuclear area greater than 35 microns 2.