Electrostimulation of a subthalamic nuclear area in Parkinson's disease
Tomskiĭ, A.A.; Bril', E.V.; Shabalov, V.A.; Fedorova, N.V.
Zhurnal Voprosy Neirokhirurgii Imeni N. N. Burdenko 3: 14-17; Discussion 17
2006
ISSN/ISBN: 0042-8817 PMID: 17125073 Document Number: 599467
The paper presents the results of application of chronic electrostimulation of the subthalamic nucleus in 15 patients with the akinetic-rigid form of Parkinson's disease. Standard UPDRS, Schwab and England, Hoehn and Yahr, and PDQ-39 rating scales were used for the clinical evaluation of motor disorders. The patients were examined before and 6 months after surgery with ON-stimulation in OFF and ON-medication. Positive results as better life quality, ameliorated motor disorders, and fewer complication of drug therapy with a two-fold reduction in the daily dose of L-dopa were obtained in the vast majority of patients (n = 14).