Virulence of Giardia lamblia isolates to laboratory mice
Romia, S.A.; Abou-Zakham, A.A.; Gamil, T.; el-Khouly, E.S.
Journal of the Egyptian Society of Parasitology 20(2): 633-638
1990
ISSN/ISBN: 1110-0583 PMID: 2230320 Document Number: 356050
Laboratory breed albino mice free of G. muris infection were inoculated with G. lamblia cysts isolated from the stools of patients with different clinical manifestations, symptomatic diarrhoeic, symptomatic non-diarrhoeic and asymptomatic cyst carriers. The virulence of various isolates was assessed by cyst excretion rate in the stools, trophozoite counts in the duodenum and histopathological lesions of jejunal mucosa. A marked variation in the virulence of cysts obtained from the 3 groups of patients was proved.