Studies on the quality of enzyme preparations (XI) --Kallidinogenase preparations
Tanimoto, T.; Ohta, M.; Kawasaki, N.; Tanaka, A.
Eisei Shikenjo Hokoku. Bulletin of National Institute of Hygienic Sciences 108: 20-25
1990
ISSN/ISBN: 0077-4715 PMID: 1364355 Document Number: 355862
Qualitative tests of 22 kinds of commercially available kallidinogenase preparations were carried out by the enzymological method. These preparations consisted of 16 kinds of tablets, 5 kinds of capsules and 1 kind of ampoule. One sample of tablet showed kallidinogenase activity less than 80% of the labeled amount by spectrophotometry, pH stat and kinin-liberating methods. All other preparations were found to have 90-120% 120% of the labeled amount by spectrophotometry using S-2266 as the substrate. Other enzymes, i.e. kininase, trypsin and chymotrypsin were found as impurities, but the cntants were very low.