An in-vitro profile of the action of four antimalarials on indigenous cases of Plasmodium falciparum malaria in Karnataka
Nagaraj, C.; Chakrabarti, N.K.; Narasimham, M.V.
Journal of Communicable Diseases 22(4): 260-263
1990
ISSN/ISBN: 0019-5138 PMID: 2098431 Document Number: 354808
In view of the emergence of chloroquine resistant Plasmodium falciparum from more and more geographical areas profiling of the responses to other available antimalarials by in vitro methods have become essential. A preliminary study undertaken in two Primary Health Centres of Karnataka State, India show the presence of strains of P. falciparum resistant to chloroquine and amodiaquine. The response for amodiaquine was poor as compared to chloroquine. The isolates were, however, sensitive to mefloquine and quinine.
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