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The effect of the spontaneous level of the chromosome aberration rate on its alterations after a single local irradiation

Kudritskiĭ, I.K.; Kuznetsov, A.I.

Tsitologiia 32(4): 394-398

1990

ISSN/ISBN: 0041-3771
PMID: 2238112
Document Number: 353235
With X-ray examinations of the stomach and duodenum, changes in chromosomal aberration frequencies in peripheral blood lymphocytes were shown to depend on the spontaneous level of these aberrations in patients exposed to a single local irradiation by 25 R. The cytogenetic efficiency of radiation exposure was found to be local in patients with the lower frequency of spontaneous chromosomal aberrations. A genetic genesis of the revealed dependence is supposed. The effect of irradiation on the correlation between radiosensitivity and radioresistance of the cytogenetic process is regarded as a possible mechanism of the appearance of the observed dependence.

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