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Thermodynamics and kinetics for the helix formation of the P3 region in Tetrahymena ribozyme

Sugimoto, N.; Monden, N.; Sasaki, M.; Yamakage, S.; Takaku, H.

Nucleic Acids Symposium Series 22: 45-46

1990

ISSN/ISBN: 0261-3166
PMID: 2101912
Document Number: 352786
The thermodynamic and kinetic results for the helix formation of the oligonucleotides, GACCGUCA and UGUCGGUC, which correspond to the sequence of the P3 region in Tetrahymena ribozyme are reported. The kinetic result suggested that the melting mechanism of the duplex of the oligonucleotides consisted of at least two steps because of a UU mismatch.

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