Serum theophylline concentrations in patients with chronic obstructive lung diseases: a comparison of 2 methods
Voshaar, T.; Schweisfurth, H.; Schöttes, C.; Prinsen, J.; Koch, H.P.
Pneumologie 44(Suppl 1): 283-284
1990
ISSN/ISBN: 0934-8387 PMID: 2195516 Document Number: 352785
A total of 120 samples of serum were obtained from 8 patients with COPD and submitted to a comparative analysis of serum theophylline levels employing the TDX and the EMIT methods of determination. At the same time, two different slow-release preparations of theophylline were compared, their kinetics investigated, and their effects tested using body plethysmography. For this open, randomized cross-over preliminary investigation, numerous inclusion and exclusion criteria were applied.