Computer simulation of the kinetics of the sodium pump
Majumdar, M.P.; Mitra, C.K.
Indian Journal of Biochemistry and Biophysics 27(3): 151-154
1990
ISSN/ISBN: 0301-1208 PMID: 2167290 Document Number: 351530
A simple kinetic model for the membrane-bound enzyme, 'Na+, K(+)-ATPase', is presented. An equation for the efflux of Na+ and influx of K+ is derived. This also explains multiple ligand binding of homospecies of these cations and competition between heterospecies of these cations. The equation is computed by a small BASIC program and its validity is sought by comparing the results with a few experimental data.