An immunoenzyme method for the quantitative determination of B-lymphocytes in human blood
Koviazina, R.N.
Laboratornoe Delo 9: 53-55
1990
ISSN/ISBN: 0023-6748 PMID: 1702864 Document Number: 350451
The author shows the advantages of estimating human blood B-lymphocytes for the diagnosis of immunodeficiency, autoimmune, and lymphoproliferative conditions with the use of tests based on the detection of surface immunoglobulin receptors. These structures are detectable by means of horseradish peroxidase-conjugated antiglobulin antibodies. Conjugates from the kits of various test systems for enzyme immunoassay were employed in this study. The developed method has proved to be highly sensitive and specific, its results are statistically reliable and in good correlation with the data of classical tests, it is economic and available, all these factors recommending the technique for wide practical use.