The use of monoclonal antibodies for the rapid detection of the hemagglutinin of the influenza a virus (H2N2) and its antibodies
Nagieva, F.G.; Nikulina, V.G.; Krasnova, N.I.; Kuliakina, M.N.; Andzhaparidze, O.G.
Voprosy Virusologii 35(4): 346-349
1990
ISSN/ISBN: 0507-4088 PMID: 2256322 Document Number: 348468
An attempt was made to study the possibility of using monoclonal antibodies to influenza A/Krasnodar/101/59 (H2N2) hemagglutinin in various modifications of enzyme immunoassay for the detection of viral antigen and antibodies in biological fluids. The experimental data indicate that competitive enzyme immunoassay with the use of 2 types of monoclonal antibodies (KR-3-30 and Kr-20) is more specific and sensitive than the traditional hemagglutination inhibition test. It may be recommended as a reference test for the detection of antihemagglutinins H2 in biological fluids.