Quantitative structure-activity relationship studies on some anticancerous, antiviral and cytostatic agents
Pandey, C.; Dwivedi, K.P.; Yadava, G.D.; Singh, V.K.; Srivastava, A.K.; Agrawal, V.K.
Indian Journal of Biochemistry and Biophysics 26(6): 405-409
1989
ISSN/ISBN: 0301-1208 PMID: 2632366 Document Number: 347380
QSAR studies using molecular connectivity and van der Waal volume have been performed on a new series of hydroxyguanidine derivatives and a series of isoindolediones. Regression analysis has shown that anticancer and antiviral activity of hydroxyguanidines as well as cytostatic activity of isoindolediones correlate well with both the structural parameters.
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