Rates of de novo fatty acid synthesis in liver, muscle and adipose tissue in non-pregnant and pregnant rats in vivo
Zimmermann, T.; Hummel, L.; Dargel, R.
Biomedica Biochimica Acta 48(4): 227-231
1989
ISSN/ISBN: 0232-766X PMID: 2751633 Document Number: 347318
Fatty acid de novo synthesis was measured quantitatively in liver, muscle and adipose tissue of non-pregnant and 21-day pregnant Uje: WIST rats in vivo. By means of 3H2O incorporation experiments the following rates of fatty acid synthesis, expressed as mumol palmitate-equivalents/animal.min, were calculated in non-pregnant and pregnant animals: liver 0.20 +/- 0.06 and 0.24 +/- 0.06; muscle 0.21 +/- 0.06 and 0.24 +/- 0.08; adipose tissue, 0.36 +/- 0.10 and 0.28 +/- 0.09, respectively. Thus, liver, muscle and adipose tissue contribute at approximately equal amounts to the summarized rate of fatty acid synthesis, which is similar in both pregnant and non-pregnant rats.