Antiarrhythmic effects of Cordyceps sinensis (Berk.) Sacc
Mei, Q.B.; Tao, J.Y.; Gao, S.B.; Xu, G.C.; Chen, L.M.; Su, J.K.
Zhongguo Zhong Yao Za Zhi 14(10): 616-8 640
1989
ISSN/ISBN: 1001-5302 PMID: 2597326 Document Number: 345772
The administration of 65% alcohol extracts of Cordyceps sinensis can counteract the arrhythmias induced by aconitine or BaCl2 in rats, and increase the tolerant dose of ouabain to produce the arrhythmias in guinea pigs. The drugs can reduce the heart rate of anesthetic rats, decreasing the contractility of isolated papillary muscle or atria in guinea pigs, but showing no effect on the automatic rhythmicity and the functional refractory period of the atria.