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Correction of disorders of the system of blood aggregation regulation by ionol in the post-resuscitation period

Rezin, V.A.

Biulleten' Eksperimental'noi Biologii i Meditsiny 108(11): 540-542

1989

ISSN/ISBN: 0365-9615
PMID: 2633815
Document Number: 345620
In the experiments on white rats resuscitated after a 7-minute mechanical asphyxia, phase disorders in the indices of the system of regulation of aggregate state of the blood in postresuscitation period have been revealed. They appear in the shape of a syndrome of disseminated intravascular blood coagulation with the development of hypercoagulation phase by the 3rd hour. Prophylactic introduction of ionol in a dose of 100 mg/kg in 48, 24 and 1 hour before the experiment prevents the development and progressing of the above syndrome.

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