Enhancing effect of whole-body ultraviolet light irradiation on Candida albicans activity of human polymorphonuclear leukocytes
Hunyadi, J.; Judak, R.; Kenderessy, A.S.; Braquet, P.; Dobozy, A.
Dermatologische Monatschrift 175(6): 326-332
1989
ISSN/ISBN: 0011-9083 PMID: 2668050 Document Number: 344008
Whole-body UV irradiation of healthy volunteers enhanced the C. albicans killing activity of the circulating polymorphonuclear granulocytes in a dose-dependent manner. This enhancing effect was inhibited by oral indomethacine treatment. The sera from irradiated subjects enhanced the killing activity of the granulocytes of untreated individuals. This effect was blocked by the administration to the system of ginkgolide B, a competitive antagonist of the platelet activating factor.