Effect of lysozyme on the functional and metabolic activity of polymorphonuclear leukocytes in the acute blood loss
Rybnikov, V.N.; Brovkina, I.L.; Uteshev, B.S.
Eksperimental'naia i Klinicheskaia Farmakologiia 67(2): 45-48
2004
ISSN/ISBN: 0869-2092 PMID: 15188762 Document Number: 584072
Acute hemorrhage leads to a decrease in the phagocyte number and index, the NBT test parameters, and the NADPH oxidase activity and to an increase in the Ca2+ ATPase activity in polymorphonuclear leukocytes on the peripheral blood. Lysozyme produces effective correction of the above parameters of the functional-metabolic activity of these cells. The drug effect is mediated by cytokines of splenocytes sticking to the glass.