A new drug sulfaton in the combined treatment of infections with sulfanilamide derivatives and diaminopyrimidine
Padeĭskaia, E.N.
Antibiotiki i Khimioterapiia 34(9): 657-662
1989
ISSN/ISBN: 0235-2990 PMID: 2692529 Document Number: 343422
Derivatives of diaminopyrimidine as potentiators of the effect of the derivatives of sulfanilamide and other antibacterial drugs are discussed. Experimental data on sulfation, a new combined preparation, based on sulfamonomethoxine (a sulfanilamide derivative) and trimethoprim (a diaminopyrimidine derivative) are presented. Brief clinical characteristics of sulfation, its administration routes, doses, dosage advantages and better tolerance as compared to co-trimethoxazole+ (biseptol) are described.