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Combined cefuroxime plus acetylcysteine in the treatment of bacterial infections of the respiratory tract

Bonavita, E.

Drugs under Experimental and Clinical Research 11(6): 361-368

1985

ISSN/ISBN: 0378-6501
PMID: 3836134
Document Number: 244895
Fifty adult patients (29 males, 21 females) suffering from respiratory tract infections with substantial production of mucus were treated with cefuroxime 1 g and acetylcysteine 300 mg administered simultaneously by i.m. injection twice daily for 10 days. Bacteriological tests were performed before and after treatment. Clinical variables (fever, cough, quantity and type of sputum, difficulty in expectorating) were evaluated, and scores ranging from 0 to 3 were designed according to an arbitrary semiquantitative scoring system. The therapeutic results obtained were positive. No side-effects were observed.

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