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In vitro activity of various antibiotics against Shigella strains

Willke, A.; Altay, G.; Ertuğrul, N.; Arman, D.

Mikrobiyoloji Bulteni 23(3): 225-230

1989

ISSN/ISBN: 0374-9096
PMID: 2487462
Document Number: 342027
The in-vitro activity of ampicillin, chloramphenicol, oxytetracycline, trimethoprim-sulfamethoxazole (TMP-SMX), cefoperazone, ceftriaxone, cefotaxime, ceftizoxime, ofloxacin, pefloxacin, ciprofloxacin and fleroxacin against clinically isolated strains of Shigella spp. (n 42) have been determined in this study. The minimum inhibitory concentrations (MICs) were established using the microtube dilution technique. In Shigella strains relatively high percentage of resistance was found against ampicillin (36.5%), chloramphenicol (34%), oxytetracycline (35%), and TMP-SMX (25.6%). The antibiotic therapy proposals are reviewed according to these results.

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