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Sensitivity of Shigella strains to bactericidal activity of human serum. I. Participation of two independently active mechanisms in bactericidal action against Shigella sonnei phase II

Mokracka-Latajka, G.; Grzybek-Hryncewicz, K.; Jankowski, S.

Acta Microbiologica Polonica 39(3-4): 111-116

1990

ISSN/ISBN: 0137-1320
PMID: 1715644
Document Number: 360785
Normal human serum is strongly bactericidal for all studied Shigella sonnei phase II (10 strains). The studied bacteria were sensitive to two alternative mechanisms of the bactericidal activity of serum factors. The first mechanism involves the action of serum in which complement (C) is activated by the studied bacteria via the classical pathway. Lysozyme did not participate in this reaction. The second mechanism involves the combined action of two factors: C activated via the alternative pathway and lysozyme.

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