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Morphofunctional characteristics of the duodenum in the early stages of experimental escherichiosis

Parkhomenko, I.G.; Salakhov, I.M.

Biulleten' Eksperimental'noi Biologii i Meditsiny 108(9): 369-372

1989

ISSN/ISBN: 0365-9615
PMID: 2692727
Document Number: 339475
Using the model of experimental colibacillosis in mice morphological, immunomorphological and morphometrical studies of duodenum 1 to 24 hours after inoculation were performed. Typical dynamics of cellular composition in the intestinal wall, accompanied with increased lymphoplasmacellular infiltration, and dystrophic changes in cells of submucosal and intermuscular neuroplexuses were found. The data obtained testify, that the infectious process at the acute state of experimental colibacillosis has an immune character (immediate hypersensitivity of local type), characterised by increasing in immunoglobulin-containing cells and including in this process of mast and endocrine cells.

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