Morphofunctional characteristics of the ovaries, thyroid gland and adrenal glands in experimental lead acetate poisoning
Vylegzhanina, T.A.; Kuznetsova, T.E.; Maneeva, O.A.; Novikov, I.I.; Ryzhkovskaia, E.L.
Meditsina Truda i Promyshlennaia Ekologiia 1993(9-10): 6-8
1993
ISSN/ISBN: 1026-9428 PMID: 8087473 Document Number: 410950
Daily doses of 50 mg/kg of lead acetate injected into the laboratory animals induce morphologic changes in the parenchyma of ovaries, thyroid gland, adrenals and compromises neural mediating processes in paraventricular and supraoptic nuclei of hypothalamus. The observed morphologic changes are similar to those characteristic for intensive functioning. Prolonged exposure to lead acetate (daily dose 10 mg/kg) results in adaptation and compensation, which preserves the functional potential of the organs. The morphologic changes in the endocrine organs do not lead to significant hormonal changes.