Effect of hyperthermia on lymphocyte plasma membrane. 3 electrolyte spin labels permeability

Koter, M.

Cytobios 58(234-35): 165-170

1989


ISSN/ISBN: 0011-4529
PMID: 2591253
Document Number: 335882
The effect of elevated temperatures on the transport of electrolyte spin labels anionic c-TEMPIR and cationic TEMPO-choline character across the porcine lymphocyte plasma membrane was investigated. Breaks in the Arrhenius plot for permeability of both spin-labels occurred at 42 to 43.degree. C. TEMPO-choline and c-TEMPIR transport are probably critical targets in hyperthermic cell killing.

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