Effect of hyperalphalipoproteinemia on structural characteristics of plasma lipoproteins according to electron paramagnetic resonance spin probe findings
Torkhovskaia, T.I.; Artemova, L.G.; Shcherbakova, I.A.; Suchkova, S.N.; Zadoia, A.A.
Biulleten' Eksperimental'noi Biologii i Meditsiny 90(12): 694-696
1980
ISSN/ISBN: 0365-9615 PMID: 6258668 Document Number: 156742
Spin probe, a stearic acid derivative, was used to study the structural features of different lipoproteins (LP) from plasma of subjects with different plasma level of high density LP (HDLP). Access of spin probe located in the internal nonpolar regions of HDLP for the reducer, ascorbic acid, was higher in hyperalphalipoproteinemia than in mean values of HDLP cholesterol concentration. An analogous effect was seen in subjects with LP of very low density. Possible causes of such differences as well as their role in biochemical reactions that proceed with LP participation are discussed.