Localization of intracellular zinc under conditions of altered permeability control of the plasma membrane
Reddy, A.G.; Devi, B.G.; Rao, S.B.; Gupta, P.D.
Cytobios 60(240): 21-26
1989
ISSN/ISBN: 0011-4529 PMID: 2517051 Document Number: 335957
Intracellular zinc was located as electron dense granules associated with the plasma membrane, endoplasmic reticular membranes, mitochondrial membranes, nuclear membranes and chromatin in Zajdela ascitic hepatoma and AK5 macrophage ascitic tumour cells. The quantity of intracellular zinc estimated by atomic emission spectrometer was different in the two cell lines. However, after loss of permeability control by the plasma membrane, involving glutaraldehyde and heat-shock treatments, the quantity of intracellular zinc was increased to almost the same extent in both cases.