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Genetic variability of antigenic structure of the Lpm-protein and alpha2-macroglobulin among non-mustelid mammals

Shumnyĭ, T.V.; Ermolaev, V.I.; Miroshnichenko, S.M.; Baranov, O.K.

Genetika 25(3): 513-520

1989

ISSN/ISBN: 0016-6758
PMID: 2474476
Document Number: 330739
The data on interspecific distribution and antigenic variability of homologues of mink Lpm-protein (Lpm) and .alpha.2M-globulin among 43 species of 6 orders of mammals are presented. Strong variability of antigenic structure of Lpm and .alpha.2M of Rodentia and Artiodactyla orders was established. This fact allows to classify the macroglobulins studied as belonging to the group of evolutionary high-speed plasma globulins. In the plasma of human and green marmoset (Cercopithecus aethiops) the only homologue of .alpha.2M was found. The lack of reaction of Lpm in above-mentioned species allows to postulate significant differences between Carnivora and Primates in the organization of this gene cluster. Unique features of antigenic variability of Lpm and .alpha.2M were also fixed among other systematical groups tested. Taken together, the data obtained stimulate scientific interest to the study of molecular organization of the Lpm and .alpha.2M gene families.

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Lennert, K.A.; Hupe, H. 1973: Pre- and postoperative behavior of serum protein inhibitors alpha-2 macroglobulin and alpha-1 antitrypsin Die Medizinische Welt 24(22): 912-915
Macedo, Aéa.M.; Machado, C.R.; Oliveira, R.P.; Pena, Sérgio.D.J. 2004: Trypanosoma cruzi: genetic structure of populations and relevance of genetic variability to the pathogenesis of chagas disease Memorias do Instituto Oswaldo Cruz 99(1): 1-12
Branson, H.E.; Endo, Y.; Fagin, A.R.; Schlutz, M. 1984: Heritable alpha 2-macroglobulin deficiency in a patient with arterial thrombosis: alpha 2-macroglobulin deficiency Irvine Journal of the National Medical Association 76(11): 1107-1112
Shilov, A.A.; Kozlov, I.V.; Chaĭka, O.V.; Kurmanova, A.G.; Zhdanov, V.M. 1987: Genetic variability of epidemic strains of influenza virus serotypes H1N1 and H3N2 during antigenic drift Voprosy Virusologii 32(4): 419-429
Armstrong, P.B.; Armstrong, M.T.; Quigley, J.P. 1993: Involvement of alpha 2-macroglobulin and C-reactive protein in a complement-like hemolytic system in the arthropod, Limulus polyphemus Molecular Immunology 30(10): 929-934
Bol shakova, G.M. 1971: Antigenic structure of the larval stages of Echinococcus and Alveococcus. I. Study of the antigenic structure of liquids from sheep and human echinococcal cysts by the methods of double diffusion in gel and electrophoresis Meditsinskaia Parazitologiia i Parazitarnye Bolezni 40(5): 522-528
Nász, I. 1988: The composed antigenic structure of the adenovirus hexon protein Virologie 39(4): 267-280
Kazachinskaia, E.I.; Ternovoĭ, V.A.; Rudzevich, T.N.; Netesov, S.V.; Chepurnov, A.A.; Razumov, I.A. 2001: Antigenic structure of Ebola virus VP35 protein Voprosy Virusologii 46(5): 25-31
Hamann, A.; Mantzoros, C.; Vidal-Puig, A.; Flier, J.S. 1995: Genetic variability in the TNF-alpha promoter is not associated with type II diabetes mellitus (NIDDM) Biochemical and Biophysical Research Communications 211(3): 833-839
Minosse, C.; Garbuglia, A.R.; Lapa, D.; Sias, C.; Zaniratti, M.S.; Capobianchi, M.R. 2010: Genetic variability in E6, E7 and L1 protein of HPV81 from HIV-1 positive women in Italy New Microbiologica 33(1): 25-35
Efimov, A.V. 1984: A new super-secondary protein structure: the alpha alpha-angle Molekuliarnaia Biologiia 18(6): 1524-1537
Mesianzhinov, V.V. 1986: A model of the secondary structure and distribution of antigenic determinants in the VP1 protein of hepatitis a virus Biofizika 31(6): 961-963
Kashtanov, S.N.; Kazakova, T.I. 1995: Genetic variability of the sable (Martes zibellinna L.) by blood protein genes Genetika 31(2): 234-238
Ogasawara, K.; Maloy, W.L.; Beverly, B.; Schwartz, R.H. 1989: Functional analysis of the antigenic structure of a minor T cell determinant from pigeon cytochrome C. Evidence against an alpha-helical conformation Journal of Immunology 142(5): 1448-1456
Swarovskaya, M.G.; Stepanova, S.K.; Marussin, A.V.; Sukhomyasova, A.L.; Maximova, N.R.; Stepanov, V.A. 2015: Genetic Variability and Structure of SNP Haplotypes in the DMPK Gene in Yakuts and other Ethnic Groups of Northern Eurasia in Relation to Myotonic Dystrophy Genetika 51(6): 724-732
Lando, G.; Berzofsky, J.A.; Reichlin, M. 1982: Antigenic structure of sperm whale myoglobin. I. Partition of specificities between antibodies reactive with peptides and native protein Journal of Immunology 129(1): 206-211
Tres, A.; Muñóz, J.R. 1977: Protease inhibitors, alpha-1-antitrypsin and alpha-2-macroglobulin, in liver processes Revista Clinica Espanola 145(6): 407-409
Paternoster, D.; Maggino, T.; Valente, S.; Pengo, V.; Ongaro, G. 1982: Changes in alpha 1-antitrypsin (AAT) and alpha 2-macroglobulin serum concentrations during treatment with oral estro-progestogens Quaderni Sclavo di Diagnostica Clinica E di Laboratorio 18(2): 132-139
Musatov, M.I.; Zhabin, S.G.; Konenkov, V.I.; Zorin, N.A. 1994: The effect of plasmin and its complexes with alpha 2-macroglobulin and alpha 2-antiplasmin on the proliferative activity of human lymphocytes Biulleten' Eksperimental'noi Biologii i Meditsiny 118(9): 304-305
Bata, J.; Colobert, L.; Biron, A.; Brune, J. 1977: Study of various serum proteins in lung cancer. Immunoglobulins A, G, M, haptoglobin, alpha-1-antitrypsin, alpha-2-macroglobulin Annales de Biologie Clinique 35(4): 297-303